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Glycogen Storage Disease IIIa in Curly-Coated Retrievers (AGL): The Second Collapse Gene Your Kennel Club Record Does Not Show

Bottom line: the Curly-Coated Retriever is the one breed in the world in which glycogen storage disease type IIIa (GSD I...
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Mucopolysaccharidosis IIIB in Schipperkes (NAGLU): The Variant Nearly One in Four Carried — and the Screening Program That Cut It Back

Bottom line: Schipperkes carry a breed-specific variant in the NAGLU gene that causes Mucopolysaccharidosis IIIB (MPS II...
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Narcolepsy in Labrador Retrievers (HCRTR2 c.1105+5G>A): The Splice Variant Behind Collapse on Excitement

Bottom line: Labrador Retrievers carry a breed-specific cause of narcolepsy — HCRTR2 c.1105+5G>A, a single base change a...
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JLPP in the Black Russian Terrier (RAB3GAP1): A Recessive Disease You Can Design Out in One Generation

Bottom line: Juvenile Laryngeal Paralysis and Polyneuropathy (JLPP) is an autosomal recessive disease of the Black Russi...
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Merle (M Locus / PMEL) in the Catahoula Leopard Dog: 10.3% of Double Merles Were Deaf, Not Two-Thirds — What the BAER Data Actually Says

Bottom line: the Catahoula Leopard Dog is the breed that the modern merle-deafness numbers were built on, and the number...
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Vitamin B12 Malabsorption (CUBN) in New Zealand Heading Dogs: the Top Finding of Massey’s 249-Dog Genome Survey — and How to Test from the US, UK and NZ

Bottom line: when a Massey University team sequenced the genomes of New Zealand's working dogs and ranked what they foun...
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Hypokalaemia in the Bombay Cat (WNK4): 7% Affected — the Highest Rate of Any Burmese-Derived Breed

Bottom line: Of every Burmese-derived breed that has been surveyed, the Bombay carries the heaviest burden of hypokalaem...
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Color Dilution Alopecia in the Doberman Pinscher: 42 of 57 Dogs — the Study That Put a Number on Blue and Fawn

Bottom line: In the Doberman Pinscher, blue and fawn are not just colors — they are the highest-risk coat colors for a h...
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Cone Degeneration in the Miniature American Shepherd: Your Parent Club Files This Test Under “Optional” — and Says the Disease Is Already Here

Bottom line: The Miniature American Shepherd's own parent club lists the Cone Degeneration (CD) DNA test under Optional ...
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PK Deficiency in the Savannah Cat: Eleven Cats Are the Whole Evidence Base — and Why That Changes What You Should Do

Bottom line: The Savannah is on the published list of breeds that should be tested for erythrocyte pyruvate kinase defic...