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Dog DNA Test: What It Can and Cannot Tell You, According to Research

What a dog DNA test really measures, how far to trust breed results, why "at risk" is not a diagnosis, and how to choose a test in the US or UK.
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Labrador Always Hungry? POMC, Guide Dogs and Cambridge Science

Bottom line: A 14-base-pair deletion in the POMC gene, reported by University of Cambridge researchers in 2016, adds on ...
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Xoloitzcuintli Hairless Gene FOXI3: Bern 2008 Study on Coats and Teeth

Bottom line: Hairlessness in the Xoloitzcuintli comes from one copy of a 7-base-pair duplication in exon 1 of the FOXI3 ...
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White Doberman Albinism and SLC45A2: Michigan State’s 20 vs 20 Dogs

Bottom line: The "white" Doberman Pinscher is a form of oculocutaneous albinism (OCA4) caused by a 4,081 bp deletion at ...
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American Staffordshire Terrier DVL2 Screw Tail: Helsinki CT Study of 285 Dogs

Bottom line: In the American Staffordshire Terrier, the screw tail variant DVL2 c.2044delC is still segregating, so a te...
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Australian Shepherd Natural Bobtail (TBXT): A 2009 23-Breed Study

Bottom line: A natural bobtail (NBT) in the Australian Shepherd comes from one copy of a single change in the TBXT gene,...
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Congenital Myasthenic Syndrome in Labradors (COLQ): The 2014 Discovery

Bottom line: Congenital myasthenic syndrome (CMS) in the Labrador Retriever is a rare, autosomal recessive failure of ne...
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American Eskimo Dog Thrombopathia (RASGRP2): What Auburn Found in 2006

Bottom line: Thrombopathia in the American Eskimo Dog is an autosomal recessive platelet disorder caused by a one-letter...
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Staffordshire Bull Terrier L-2-HGA (L2HGDH): AHT Research and 27 Dogs

Bottom line: L-2-hydroxyglutaric aciduria (L-2-HGA) is an autosomal recessive brain disease in which a faulty L2HGDH gen...
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French Spaniel Acral Mutilation Syndrome (GDNF): Montreal to Rennes 2016

Bottom line: Acral mutilation syndrome (AMS) in French Spaniels is an autosomal recessive sensory neuropathy: from a few...