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Hemophilia A (F8) in Boxers: Auburn’s 2014 Family and the DNA Test Gap

Bottom line: The only published Boxer cause of hemophilia A is a single-letter change in the factor VIII gene (F8), repo...
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Rhodesian Ridgeback Hemophilia B (F9): The 2011 Hannover G244E Study

Bottom line: Hemophilia B in the Rhodesian Ridgeback has a named cause: the F9 variant c.731G>A, which turns glycine 244...
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Toy Fox Terrier Congenital Hypothyroidism (TPO): MSU’s 2003 Discovery

Bottom line: Congenital hypothyroidism with goiter (CHG) in Toy Fox Terriers is an autosomal recessive puppy disorder ca...
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Tibetan Terrier Pituitary Dwarfism (LHX3): What the 2021 MSU Study Found

Bottom line: Pituitary dwarfism in Tibetan Terriers is an autosomal recessive disorder caused by the same LHX3 deletion ...
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Scottie Lion Jaw (CMO) and SLC37A2: What CT Scans and DNA Data Show

Bottom line: Craniomandibular osteopathy (CMO, or "lion jaw") is a painful overgrowth of bone in the jaw and skull of gr...
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Open-Angle Glaucoma in Beagles: 50 Years of Research and ADAMTS10

Bottom line: Primary open-angle glaucoma (POAG) in Beagles is caused by a single change in the ADAMTS10 gene, G661R, ide...
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Are All Scottish Folds Affected? SFOCD and TRPV4 Studies, 1999–2025

Bottom line: The folded ear of the Scottish Fold and the bone and cartilage disease called Scottish Fold osteochondrodys...
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Australian Cattle Dog Myotonia Congenita: One Ontario Case and CLCN1

Bottom line: Myotonia congenita in the Australian Cattle Dog rests on one dog. A 2007 University of Guelph study of a pu...
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Finnish Lapphund Pompe Disease (GSD II): What Helsinki Research Shows

Bottom line: Pompe disease (glycogen storage disease type II, GSD II) in the Finnish Lapphund is an autosomal recessive ...
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Yorkshire Terrier Color Dilution Alopecia: Case Reports and MLPH Genetics

Bottom line: Color dilution alopecia (CDA) has been described in Yorkshire Terriers in case reports since 1988, includin...